Ionis Pharmaceuticals (formerly known as Isis Pharmaceuticals) is a company that discovers and develops RNA-targeted medicines. It offers SPINRAZA, an injection for children and adults with spinal muscular atrophy (SMA); TEGSEDI, a transthyretin-directed antisense oligonucleotide medicine; WAYLIVRA, a medicine used to treat familial chylomicronaemia syndrome (FCS); and other solutions.