Alnylam Pharmaceuticals

Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The Company’s pipeline focuses in three strategic therapeutic areas (STArs): genetic medicines, with a pipeline of RNAi therapeutics for the treatment of rare diseases; cardio-metabolic disease, with a pipeline of RNAi therapeutics toward genetically validated, liver-expressed disease in cardiovascular and metabolic diseases, and hepatic infectious disease, with a pipeline of RNAi therapeutics for treatment of hepatic infectious diseases. Its products include Patisiran (ALN-TTR02), Revusiran (ALN-TTRsc), ALN-AT3, ALN-CC5, ALN-AS1, ALN-AAT, ALN-GO1, ALN-TMP, ALN-PCS, ALN-PCSsc, ALN-AC3, ALN-ANG, ANGPTL3, ALN-HBV, ALN-HDV and ALN-PDL. It is developing two investigational RNAi therapeutic candidates for TTR-Mediated Amyloidosis (ATTR): patisiran and revusiran.

Company Growth (employees)
Cambridge, US
Size (employees)
514 (est)
Alnylam Pharmaceuticals was founded in 2002 and is headquartered in Cambridge, US

Key People/Management at Alnylam Pharmaceuticals

Saraswathy (Sara) Nochur

Saraswathy (Sara) Nochur

Senior Vice President, Regulatory Affairs & Quality Assurance
Muthiah (Mano) Manoharan

Muthiah (Mano) Manoharan

Senior Vice President, Drug Discovery
Lubomir (Lubo) Nechev

Lubomir (Lubo) Nechev

Vice President, Process Sciences
Mary Beth DeLena

Mary Beth DeLena

VP, Legal
David Bartel

David Bartel

Scientific Advisory Board and Founder

Alnylam Pharmaceuticals Office Locations

Alnylam Pharmaceuticals has offices in Cambridge, Windsor and Maidenhead and Zug
Cambridge, US (HQ)
300 Third St
Zug, CH
19 Dammstrasse
Windsor and Maidenhead, GB
Braywick Rd

Alnylam Pharmaceuticals Financials and Metrics

Alnylam Pharmaceuticals Financials


Net income (Q2, 2017)

(118.4 m)

EBIT (Q2, 2017)

(120.5 m)

Market capitalization (13-Dec-2017)

11.5 b

Cash (30-Jun-2017)

408.7 m


11.2 b
Alnylam Pharmaceuticals's current market capitalization is $11.5 b.
USDFY, 2013FY, 2014FY, 2015FY, 2016

R&D expense

382.4 b

General and administrative expense

89.4 b

Operating expense total

471.7 b


(92.9 m)(405 m)(296 m)(424.6 b)
USDQ3, 2013Q1, 2014Q2, 2014Q3, 2014Q1, 2015Q2, 2015Q3, 2015Q1, 2016Q2, 2016Q3, 2016Q1, 2017Q2, 2017

R&D expense

34.5 m43.8 m44.7 m46.3 m58 m67 m68.6 m96.3 m83.2 m97.9 m87 m90.6 m

General and administrative expense

6.8 m8.9 m11.5 m9.9 m12.7 m14.6 m16 m21.1 m18 m22.4 m38.5 m45.8 m

Operating expense total

41.2 m277.3 m52.3 m56.2 m70.8 m81.6 m84.7 m117.4 m101.2 m120.3 m125.5 m136.4 m


(32.2 m)(269.1 m)(45 m)(45.2 m)(52.2 m)(72.9 m)(78.3 m)(110 m)(92.5 m)(106.7 m)(106.5 m)(120.5 m)
USDFY, 2013FY, 2014FY, 2015FY, 2016


53.2 m75.2 m180.9 m193.6 m

Accounts Receivable

17.9 m


3.9 m9.7 m16.6 m21.7 m

Current Assets

254 m746.4 m1.1 b671.9 m
USDQ3, 2013Q1, 2014Q2, 2014Q3, 2014Q1, 2015Q2, 2015Q3, 2015Q1, 2016Q2, 2016Q3, 2016Q1, 2017Q2, 2017


11.8 m350.6 m80.7 m82.7 m306.6 m151.3 m149.2 m231.3 m271.1 m168.5 m171.1 m408.7 m

Current Assets

199.2 m674.1 m665.1 m643 m1.1 b1 b1 b1.1 b888.1 m747.6 m597.2 m960.7 m


17 m15.7 m17 m18.8 m21.2 m25.2 m26.3 m36.8 m55.4 m74.2 m130 m147.5 m

Total Assets

447.5 m1.1 b1 b986.4 m1.6 b1.5 b1.4 b1.3 b1.4 b1.3 b1.1 b1.4 b
USDFY, 2013FY, 2014FY, 2015FY, 2016

Net Income

(89.2 m)(360.4 m)(290.1 m)(410.1 m)

Depreciation and Amortization

10.2 m11.9 m19.1 m15.1 m

Accounts Payable

1.8 m8.8 m1.7 m10.1 m

Cash From Operating Activities

(68.7 m)(165.6 m)(189.1 m)(307.7 m)
USDQ3, 2013Q1, 2014Q2, 2014Q3, 2014Q1, 2015Q2, 2015Q3, 2015Q1, 2016Q2, 2016Q3, 2016Q1, 2017

Net Income

(29.7 m)(250.9 m)(44.1 m)(44 m)(50.8 m)(71.8 m)(76.8 m)(103 m)(90.1 m)(104.1 m)(107.3 m)

Accounts Payable

6.2 m5.2 m15.5 m15.7 m14.3 m17.4 m12.8 m23.1 m25.4 m
Y, 2017


-93 x

Financial Leverage

1.3 x
Show all financial metrics

Alnylam Pharmaceuticals Market Value History

Alnylam Pharmaceuticals Median Salaries

Source: 19 public H-1B filings from Alnylam Pharmaceuticals

Alnylam Pharmaceuticals's Web-traffic and Trends

Alnylam Pharmaceuticals Online and Social Media Presence

Alnylam Pharmaceuticals Company Life and Culture

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