TARIS Biomedical was founded in 2008 in response to a long-standing clinical need for a convenient, safe, and effective way to treat bladder disease locally. Encouraged by the effectiveness of local bladder instillations but frustrated by the need for frequent repeated dosing due to normal bladder emptying, urologists expressed a desire for a better approach. TARIS’s solution is a brilliantly simple and elegant system that can continuously deliver drug in the bladder. It was conceived in the laboratories of internationally renowned biotechnology entrepreneurs Robert Langer and Michael Cima at the Massachusetts Institute of Technology. Since its inception, TARIS has applied this technology in the development of products with a potential to provide effective and well-tolerated therapeutics for difficult-to-treat urological conditions. TARIS’s first program, LiRIS (lidocaine releasing intravesical system), for the treatment of interstitial cystitis/bladder pain syndrome was acquired by Allergan, in August of 2014. This sale was an important validation of our approach; TARIS has now turned its focus to developing a broad portfolio of products addressing significant unmet need in the treatment of several debilitating bladder diseases, including bladder cancer and overactive bladder.