SilcsBio is a company that provides computer-aided drug design (CADD) software solutions. It develops site identification by ligand competitive saturation (SILCS); 3D frag maps that visualize protein surface; CGENFF, programs that generate parameters and topology information of drug-like molecules; single-step free energy perturbation (SSFEP), software for energy calculations; etc. The company also offers homology modeling, molecular dynamics simulations, lead optimization, binding hotspot identification, and other services.