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Horizon Discovery is a revenue-generating life science group supplying research tools to organizations engaged in translational genomics research and the development of personalized medicines. Horizon serves various organizations including major pharmaceutical, biotechnology, and diagnostic companies as well as leading academic research centers. The Group core capabilities are built around its proprietary translational genomics platform, a high-precision and flexible suite of gene editing tools able to alter almost any endogenous gene sequence of human or mammalian cell lines. Horizon offers a portfolio of products, almost all of which are based on the application of gene editing to generate cell lines that accurately model the disease-causing mutations found in genetically based diseases. These ‘patients-in-a-test-tube’ are being used by customers to identify the effect of individual or compound genetic mutations on drug activity, patient responsiveness, and resistance, which may lead to the successful prediction of which patient sub-groups will respond to currently available and future drug treatments. In addition, it provides custom cell line and in vivo model generation services for research and bioproduction applications, quantitative molecular reference standards, in vivo disease models, and contract research and custom screening services.

TypePublic
Founded2005
HQWaterbeach, GB
Websitehorizondiscovery.com
Employee Ratings3.5

Latest Updates

Employees (est.) (Dec 2018)398
Job Openings31
Revenue (FY, 2018)£58.7 M(+69%)
Share Price (Dec 2020)£1.8
Cybersecurity ratingBMore

Key People/Management at Horizon Discovery

Darrin Disley

Darrin Disley

CEO
Richard Vellacott

Richard Vellacott

Chief Financial Officer & Deputy Chief Executive Officer
Terry Pizzie

Terry Pizzie

Head of Commercial Operations
Heather Hayes

Heather Hayes

Head of Human Resources
Jurgen Harter

Jurgen Harter

Global Head of IT & Informatics
Jon Moore

Jon Moore

Chief Scientific Officer, Head of Translational Science
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Horizon Discovery Office Locations

Horizon Discovery has offices in Waterbeach, Boyertown, Lafayette and St. Louis
Waterbeach, GB (HQ)
Cambridge Research Park Beach Dr
Boyertown, PA, US
Boyertown, PA 19512, USA
Lafayette, CO, US
2650 Crescent Dr #100
St. Louis, MO, US
2033 Westport Center Dr
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Horizon Discovery Financials and Metrics

Horizon Discovery Revenue

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Horizon Discovery's revenue was reported to be £58.73 m in FY, 2018
GBP

Revenue (FY, 2018)

58.7m

Gross profit (FY, 2018)

39.5m

Gross profit margin (FY, 2018), %

67.3%

Net income (FY, 2018)

(35.8m)

EBITDA (FY, 2018)

(32.5m)

EBIT (FY, 2018)

(40.7m)

Market capitalization (23-Dec-2020)

303.0m

Closing stock price (23-Dec-2020)

1.8

Cash (31-Dec-2018)

26.7m
Horizon Discovery's current market capitalization is £303 m.
GBPFY, 2013FY, 2014FY, 2015FY, 2016FY, 2017FY, 2018

Revenue

6.6m11.9m20.2m24.1m35.0m58.7m

Revenue growth, %

79%69%

Cost of goods sold

3.2m5.4m10.2m11.0m13.6m19.2m

Gross profit

3.4m6.6m10.0m13.1m21.4m39.5m
GBPFY, 2013FY, 2014FY, 2015FY, 2016FY, 2017FY, 2018

Cash

4.2m18.5m25.1m6.1m28.1m26.7m

Accounts Receivable

1.4m3.9m7.0m10.2m14.4m16.0m

Inventories

453.0k1.3m1.8m2.0m2.6m2.5m

Current Assets

6.7m25.8m36.5m20.6m49.7m51.4m
GBPFY, 2013FY, 2014FY, 2015FY, 2016FY, 2017FY, 2018

Net Income

(3.0m)(5.9m)(9.9m)(11.4m)(11.0m)(35.8m)

Cash From Operating Activities

(2.2m)(6.5m)(11.0m)(8.2m)(13.9m)1.5m

Cash From Financing Activities

3.7m37.6m24.3m141.0k77.6m1.4m

Net Change in Cash

496.6k14.3m6.6m(19.4m)21.5m(1.9m)
GBPFY, 2013

Financial Leverage

1.4 x
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Horizon Discovery Cybersecurity Score

Cybersecurity ratingPremium dataset

B

85/100

SecurityScorecard logo

Horizon Discovery Environment, Social & Governance (ESG) Ratings

CSRHub ESG ratingPremium dataset

40-49

out of 100

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Horizon Discovery Online and Social Media Presence

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Horizon Discovery News and Updates

Horizon Discovery Group plc: Pre-Close Trading Update

Horizon Discovery Group plc

Activist ValueAct raises stake in Horizon Discovery

Activist hedge fund ValueAct Capital has nearly doubled its stake in Horizon Discovery Group , buying an additional 7.5 million shares from Woodford Investment Management.

Horizon Discovery Group Plc: Interim Results for the Six Months Ended 30 June 2018

HORIZON DISCOVERY GROUP PLC (“Horizon”, “the Group” or “the Company”)

Horizon Discovery Blogs

Cell Panel Screens vs Functional Genomic Screens: What should I use?

Choosing the right cell-based screen from the plethora of options available can quickly become a complicated decision process. Here, we review two of the major options: cell panel and functional genomic screening. Cell panel screening provides drug response data across panels of genomica…

Top peer reviewed scientific articles using HAP1 cell lines

Can I use the HAP1 cell line for my research? The HAP1 cell line has been applied across a wide range of biological processes, such as DNA damage repair pathway and stress responses, as well as in disease modeling. These selected articles show the broad applicability of the HAP1 cell line, and prov…

Using CRISPR for target identification and target validation

The discovery of the CRISPR‐Cas system in bacteria has initiated an impressive array of innovations that have enabled the use of the RNA‐guided Cas9 nuclease in functional genomic screens. At Horizon, we have embraced these developments, as they provide new opportunities for drug target …

Why you should use 3D models for high throughput screening

The clinical success rate of new oncology drugs is only 3.4% compared to 20.9% in other disease types (Wong et al,2018). One contributing factor to this issue is the testing systems used, with two-dimensional (2D) monolayer assay formats as the traditional mainstay of high throughput scr…

Efficient breeding of rat and mouse models

5 keys to success for colony management• Direct access to the actual colony managers working with your colony• Dedicated project manager communicating key updates and timelines• Colony Management Software tracking your colony progress• Industry experienced animal technicians, colony ma…

HAP1 Cell Lines - are they the right cell model for you?

HAP1 cell lines are a popular choice to validate a range of research experiments, but if you’ve never used them before, you want to be sure they are right for you.
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Horizon Discovery Frequently Asked Questions

  • When was Horizon Discovery founded?

    Horizon Discovery was founded in 2005.

  • Who are Horizon Discovery key executives?

    Horizon Discovery's key executives are Darrin Disley, Richard Vellacott and Terry Pizzie.

  • How many employees does Horizon Discovery have?

    Horizon Discovery has 398 employees.

  • What is Horizon Discovery revenue?

    Latest Horizon Discovery annual revenue is £58.7 m.

  • What is Horizon Discovery revenue per employee?

    Latest Horizon Discovery revenue per employee is £147.6 k.

  • Who are Horizon Discovery competitors?

    Competitors of Horizon Discovery include Lionex, ArcanaBio and Genematrix.

  • Where is Horizon Discovery headquarters?

    Horizon Discovery headquarters is located at Cambridge Research Park Beach Dr, Waterbeach.

  • Where are Horizon Discovery offices?

    Horizon Discovery has offices in Waterbeach, Boyertown, Lafayette and St. Louis.

  • How many offices does Horizon Discovery have?

    Horizon Discovery has 4 offices.