CHA Vaccine Institute ((주)차백신연구소, formerly known as Dubeel) is a research-oriented biotechnology company. It researches and develops vaccine products targeting infectious diseases as well as chronic diseases. It creates 3rd gen. Hepatitis B vaccine (HBV), HBV therapeutic vaccine, zoster vaccine, flu vaccine, adjuvants, and recombinant mannan-binding lectins. The company also has a recombinant antigen development platform with this platform the company has developed an improved prophylactic vaccine for infectious diseases and a therapeutic vaccine for chronic disease.