![]() Ionis Pharmaceuticals Ionis Pharmaceuticals (formerly known as Isis Pharmaceuticals) is a company that discovers and develops RNA-targeted therapeutics. | ![]() Sylentis Sylentis is a biotechnology company focused on the development of ophthalmic drugs and therapies based on RNAi (gene silencing) technology. | ![]() AnGes AnGes is a biopharmaceutical company specializing in R&D and practical application of genetic medicine. | |
Founding Date | Founding Date 1989 | Founding Date 2006 | Founding Date 1999 |
Type | Type Public | Type Private | Type Public |
Tags | |||
Locations | Locations Tres Cantos, ES HQ Madrid, ES Mountain View, US | Locations Ibaraki, JP HQ Fujisawa, JP Ibaraki, JP Kawasaki, JP Minato City, JP Bethesda, US | |
Employees | Employees 1,40231% increase | Employees 51 | Employees 5562% decrease |
Valuation ($) | Valuation ($) 6.3 b | Valuation ($) N/A | Valuation ($) 78.3 m |
Financial | |||
Revenue (est.) | Revenue (est.) $943.7m (FY, 2025) | Revenue (est.) N/A | Revenue (est.) ¥874.1m (FY, 2025) |
Cost of goods | Cost of goods $15.9m (FY, 2025) | Cost of goods N/A | Cost of goods ¥499.9m (FY, 2025) |
Gross profit | Gross profit $927.8m (FY, 2025) | Gross profit N/A | Gross profit ¥374.2m (FY, 2025) |
Net income | Net income ($381.4m) (FY, 2025) | Net income N/A | Net income (¥5.1b) (FY, 2025) |

Sylentis is a biotechnology company focused on the development of ophthalmic drugs and therapies based on RNAi (gene silencing) technology.
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AnGes is a biopharmaceutical company specializing in R&D and practical application of genetic medicine.
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