XTuit Pharmaceuticals, Inc. is a biopharmaceutical company developing novel microenvironment-activated therapeutics targeting key mechanisms resulting in hypoxia, decreased drug uptake, drug resistance, and decreased immune response. The Company’s proprietary drug development pipeline and integrated, sophisticated clinical biomarker platform will be used for accelerated clinical development across selected cancers and fibrotic disorders. XTuit’s compounds act through pleiotropic mechanisms to inhibit extracellular matrix synthesis and stabilization, and to silence activated stromal cells, including cancer-associated fibroblasts and stellate cells. As a result, XTuit compounds alleviate hypoxia and enable enhanced drug uptake through solid stress reduction. Moreover, the drugs have been shown to down-regulate stroma-induced tumor and inflammation signaling pathways to overcome treatment resistance. XTuit’s first two lead series are being developed for early clinical proof-of-concept in liver diseases and cancer.
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HQWaltham, US
Size (employees)10 (est)
XTuit Pharmaceuticals was founded in 2011 and is headquartered in Waltham, US
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XTuit Pharmaceuticals Office Locations

XTuit Pharmaceuticals has an office in Waltham
Waltham, US (HQ)
35 Gatehouse Dr
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XTuit Pharmaceuticals Financials and Metrics

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Founding Date


XTuit Pharmaceuticals total Funding

$26 m

XTuit Pharmaceuticals latest funding size

$22 m

Time since last funding

3 years ago

XTuit Pharmaceuticals investors

XTuit Pharmaceuticals's latest funding round in June 2015 was reported to be $22 m. In total, XTuit Pharmaceuticals has raised $26 m
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XTuit Pharmaceuticals Company Life and Culture

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