Spyryx Biosciences

OverviewSuggest Edit

Spyryx Biosciences is a biopharmaceutical company which provides peptide therapeutics for obstructive lung diseases. The Company focuses on cystic fibrosis and obstructive pulmonary diseases. Its main product is spx-101 which replaces splunc1 in cf to restore airway hydration.
HQDurham, NC, US

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Employees (est.) (Oct 2021)1
Cybersecurity ratingAMore
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Key People/Management at Spyryx Biosciences

Tim Shannon

Tim Shannon

Timm Crowder

Timm Crowder

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Spyryx Biosciences Office Locations

Spyryx Biosciences has an office in Durham
Durham, NC, US (HQ)
801 Capitola Dr
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Spyryx Biosciences Financials and Metrics

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Founding Date


Spyryx Biosciences total Funding

$18.2 m

Spyryx Biosciences latest funding size

$18.2 m

Time since last funding

6 years ago

Spyryx Biosciences investors

Spyryx Biosciences's latest funding round in May 2015 was reported to be $18.2 m. In total, Spyryx Biosciences has raised $18.2 m
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Spyryx Biosciences Cybersecurity Score

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Spyryx Biosciences Online and Social Media Presence

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Spyryx Biosciences Blogs

Without getting too complex, it [SPX-101] helps patients clear mucus from their lungs.

11. Jun / Monday Morning Thoughts – Blog Post by Gunnar Esiason A few medications are charging through the drug pipeline that could one day, very soon, broadly impact the CF community. First we have this guy, SPX-101. SPX-101 is an ENaC Modulator. Without getting too complex, it helps patients clear…

SPX-101 is Stable In and Retains Function After Exposure to Cystic Fibrosis Sputum

The science team at Spyryx has recently published an open-access article in the Journal of Cystic Fibrosis, supporting the stability of SPX-101 in the protease-rich environment of cystic fibrosis airways. Here, we demonstrate SPLUNC1, the natural allosteric regulator of ENaC, is degraded by multiple…

Phase 2 Study Shows Promising Results for Potential Mucus Clearance Drug

A new drug intended to make it easier to clear mucus from the lungs of people with cystic fibrosis showed promising results in a Phase 2 clinical trial. The drug, called SPX-101, blocks the overactive sodium channels that line CF lung cells. – Published on June 7, 2018 | Cystic Fibrosis Foundation® …

Spyryx SPX-101 Phase 2 HOPE-1 Trial Shows Improvement in Lung Function in Patients with Cystic Fibrosis via Novel Modulation of ENaC

Inhaled drug can be used regardless of a patient’s particular CF mutation. – DURHAM, N.C., June 6, 2018 /PRNewswire/ — Today Spyryx shared positive data for the first cohort of the SPX-101 Phase 2 clinical trial HOPE-1 (Hydration for Optimal Pulmonary Effectiveness), which showed that treatment with…

Spyryx Biosciences Frequently Asked Questions

  • When was Spyryx Biosciences founded?

    Spyryx Biosciences was founded in 2013.

  • Who are Spyryx Biosciences key executives?

    Spyryx Biosciences's key executives are Tim Shannon and Timm Crowder.

  • How many employees does Spyryx Biosciences have?

    Spyryx Biosciences has 1 employees.

  • Who are Spyryx Biosciences competitors?

    Competitors of Spyryx Biosciences include Pacific Medical Centers, Verve Therapeutics and Stealth BioTherapeutics.

  • Where is Spyryx Biosciences headquarters?

    Spyryx Biosciences headquarters is located at 801 Capitola Dr, Durham.

  • Where are Spyryx Biosciences offices?

    Spyryx Biosciences has an office in Durham.

  • How many offices does Spyryx Biosciences have?

    Spyryx Biosciences has 1 office.